Guide — Med-Surg
Skin Cancer & Melanoma Nursing Care
Skin cancer is the most common cancer — and the most preventable and most curable when caught early. Two of the three are slow and local; melanoma is the one that kills, and it announces itself with a changing mole. Nurses are positioned to catch it and to teach the prevention that stops it.
9 min read · Med-Surg
Educational use only. Biopsy, staging, and treatment decisions belong to dermatology and oncology — follow their plan. This guide supports assessment, prevention teaching, and perioperative care. This material supports nursing education and exam review. It is not medical advice and is not a substitute for clinical judgment, institutional policy, or medical direction. Always follow facility protocols and current provider orders.
Overview — Three Cancers
Basal cell carcinoma (BCC) is the most common skin cancer — slow-growing, rarely metastasizes; classically a pearly, translucent papule with rolled borders and telangiectasias that may ulcerate. Squamous cell carcinoma (SCC) is the second most common — a scaly, crusted, or ulcerated firm lesion on sun-exposed skin (and lips/ears); it can metastasize, especially in the immunosuppressed.
Melanoma is less common but the deadliest — arising from melanocytes, it can metastasize early and widely. It often presents as a new or changing pigmented lesion. The depth of invasion (Breslow depth) drives prognosis — which is exactly why early detection saves lives.
Key Concepts
ABCDE of melanoma
Asymmetry · Border irregularity · Color variation (multiple shades) · Diameter > 6 mm (pencil eraser) · Evolving (changing in size, shape, color, or new symptoms like itching/bleeding). The “ugly duckling” sign — a mole that looks different from the person’s others — is a powerful complement: trust it.
Risk factors
UV exposure (sun and tanning beds), history of sunburns (especially blistering, childhood), fair skin that burns easily, many or atypical moles, family/personal history, and immunosuppression (transplant patients have markedly higher SCC risk). Most skin cancer is UV-driven and therefore preventable.
Diagnosis and treatment
Diagnosis is by biopsy (suspicious melanoma gets full-thickness/excisional biopsy, not a shave, to measure depth). Treatment ranges from local excision and Mohs surgery (BCC/SCC) to wide local excision with sentinel lymph node biopsy for melanoma, plus immunotherapy/targeted therapy for advanced disease.
Don’t forget hidden sites
Melanoma also appears where the sun doesn’t reach and in darker skin tones — palms, soles, under nails (subungual), and mucous membranes (acral lentiginous melanoma). A new dark streak under a nail or a non-healing sole lesion deserves attention.
Assessment Findings
During any skin assessment, note new, changing, non-healing, or bleeding lesions; apply ABCDE and the ugly-duckling sign to pigmented lesions; and inspect the high-yield spots — face, ears, lips, scalp, dorsal hands, lower legs, and the hidden acral sites. Document size, color, borders, and any change over time (a photo helps). Identify risk factors and review the patient’s sun history and self-exam habits. Post-operatively, assess the excision/graft site, margins status, and for melanoma, the nodal basin and signs of recurrence on follow-up.
Nursing Priorities
Catch it and refer it
Flag suspicious lesions and ensure timely dermatology follow-up — a nurse’s “this mole has changed” can be lifesaving. Teach and reinforce monthly skin self-examination.
Support the procedure
Prepare patients for biopsy/excision/Mohs (often outpatient), provide wound care and site instructions, manage pain, and watch for infection or bleeding. For larger excisions or grafts, give graft/flap care and activity limits.
Drive prevention hard
Sun-safety teaching is the highest-impact intervention: broad-spectrum SPF 30+ sunscreen reapplied every 2 hours, sun avoidance at peak hours (10–4), protective clothing and hats, and NO tanning beds. Stress that prevention also protects against recurrence and second cancers.
Support through a cancer diagnosis
For melanoma especially, provide emotional support, coordinate oncology care, and prepare patients for staging, surveillance, and the systemic therapies (immunotherapy) used in advanced disease, including their side effects.
Therapeutic Communication Considerations
Reactions split two ways: some patients dismiss skin cancer as “just a spot,” others hear “melanoma” and assume a death sentence. Calibrate — emphasize how curable early disease is while taking suspicious lesions seriously enough to act. Sun-safety teaching can feel like scolding; frame it as protecting the skin they have rather than blaming past sunburns. For a melanoma diagnosis, pace information, provide hope grounded in early-stage cure rates and modern therapies, and connect to oncology support.
Patient & Family Education
Teach monthly skin self-exams using ABCDE and the ugly-duckling rule, and to report new, changing, non-healing, or bleeding lesions promptly — including under nails and on soles. Drill sun protection: sunscreen SPF 30+ reapplied every 2 hours and after swimming/sweating, shade and protective clothing, avoiding midday sun, and never using tanning beds. For those treated, stress lifelong dermatology surveillance (history of one skin cancer raises the risk of another), and for melanoma survivors, the follow-up schedule and what recurrence might look like. Encourage protecting children, since childhood sun exposure drives lifetime risk.
NCLEX Pearls
- ✦ABCDE: Asymmetry, Border irregularity, Color variation, Diameter >6 mm, Evolving — plus the ugly-duckling sign.
- ✦BCC = pearly papule with rolled borders/telangiectasias (rarely spreads); SCC = scaly/ulcerated, can metastasize; melanoma = deadliest, spreads early.
- ✦Suspicious melanoma gets excisional (full-thickness) biopsy to measure depth — not a shave biopsy.
- ✦UV exposure (sun + tanning beds) is the main modifiable risk; immunosuppressed/transplant patients have high SCC risk.
- ✦Prevention = SPF 30+ reapplied q2h, protective clothing, avoid peak sun, no tanning beds; teach monthly self-exams.
Related Resources
Standards & sources
Fact-checked Jun 21, 2026This page is written to align with Academy of Medical-Surgical Nurses (AMSN) · Current medical-surgical nursing standards. It is an educational summary, not a citation of any single document — always verify specific doses, values, and protocols against current guidelines and your facility policy. How we source content →
