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Apex Nursing

Chart — Med-Surg

Cirrhosis Complications Chart

Every complication of cirrhosis traces to one of two root failures — portal hypertension (blocked blood flow) or lost liver function (failed chemistry). Group them that way and the disease stops being a list to memorize.

Educational use only. Treatment of each complication follows provider orders and protocol; this chart maps cause to nursing response, not prescriptions. This material supports nursing education and exam review. It is not medical advice and is not a substitute for clinical judgment, institutional policy, or medical direction. Always follow facility protocols and current provider orders.

Complications by Root Cause

ComplicationRoot CauseWhat You SeeNursing Response
Esophageal / gastric varicesPortal hypertensionPainless massive hematemesis or melena; the fragile collateral veins ruptureEmergency: large-bore IV, type & cross, volume; anticipate endoscopic banding; non-selective beta-blockers as prophylaxis
AscitesPortal hypertension + low albuminAbdominal distension, shifting dullness, weight gain, dyspnea from pressure on the diaphragmSodium restriction, diuretics (spironolactone-based), daily weight & girth; paracentesis for tense ascites (albumin after large taps)
Spontaneous bacterial peritonitis (SBP)Infected ascitic fluidFever, abdominal pain, and worsening encephalopathy in an ascitic patient — sometimes subtleDiagnostic paracentesis (cell count/culture), antibiotics; a high-suspicion, escalate-early complication
Hepatic encephalopathyLost ammonia detoxificationConfusion, altered LOC, asterixis (flapping tremor), elevated ammonia; GI bleeding worsens itLactulose titrated to 2–3 soft stools/day; rifaximin per orders; identify and treat triggers (bleeding, infection, constipation)
Coagulopathy & bleedingLost clotting-factor synthesis + low plateletsProlonged PT/INR, easy bruising, mucosal bleedingBleeding precautions; vitamin K / FFP / platelets per orders; avoid IM injections and trauma
Jaundice & pruritusLost bilirubin processingYellow skin/sclera, dark urine, clay stools, intense itchingSkin care, cool environment, antipruritics per orders; protect skin from scratching breakdown
Hepatorenal syndromeAdvanced liver failure → renal hypoperfusionRising creatinine, falling urine output without primary kidney disease — a late, ominous signMonitor renal function and I&O; avoid nephrotoxins; escalate — it signals advanced decompensation

Exam Traps

  • Hematemesis in cirrhosis = variceal bleed (emergency) — and it also drives up ammonia, worsening encephalopathy.
  • Fever + abdominal pain + new confusion in an ascitic patient = spontaneous bacterial peritonitis.
  • Lactulose titrates to 2–3 soft stools/day; improving mental status confirms it's working.
  • Rising creatinine with falling output and no kidney disease = hepatorenal syndrome, a late sign.
  • Bleeding precautions throughout — the cirrhotic liver can't make clotting factors.

Related Resources

Standards & sources

Fact-checked Jun 21, 2026

This page is written to align with Academy of Medical-Surgical Nurses (AMSN) · Current medical-surgical nursing standards. It is an educational summary, not a citation of any single document — always verify specific doses, values, and protocols against current guidelines and your facility policy. How we source content →